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OECD Alternative Methods To Replace Existing Animal Test

This article was originally published in The Rose Sheet

Executive Summary

The Organisation for Economic Co-operation and Development, the international group charged with finding alternatives to animal tests, plans to eliminate animal test TG 401 and replace it with a revised Up-and-Down Procedure (TG 425) and two other testing methods in July, the National Toxicology Program Advisory Committee on Alternative Toxicological Methods said Nov. 28.

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OECD To Present Animal Alternative Tests At Fall Consultation Meeting

Four animal alternative test guidelines will be considered by the Organisation for Economic Co-operation and Development at an expert consultation meeting Oct. 13-15 meeting in Bethesda, Md., the group said

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Interagency Center for the Evaluation of Alternative Toxicological Methods seeking public comment on its report on the revised Up-and-Down Procedure of acute oral toxicity testing in animals, National Institute for Environmental Health Sciences announces in Feb. 7 Federal Register notice. Comment deadline is March 25. Available on 1ICCVAM's Web site, the report includes scientific peer review of revised UDP and final test guidelines and will be transmitted to U.S. federal agencies following comment period. ICCVAM reviewed the procedure, an alternative to conventional means of evaluating LD50, in an October report (2"The Rose Sheet" Oct. 15, 2001, p. 9). UDP uses fewer animals than conventional methods...

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